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Other Topics: HPV Picture Symptom Wart, HPV Vaccine, HPV and Pregnancy, HPV Shot, HPV Vaccines, Cervical Cancer Human Papilloma Virus, Human Papilloma Virus, Cervical Dysplasia and Fertility, Abnormal Pap Smear Result, Genital Wart Picture

HSR Research > Mild cervical dysplasia

Mild cervical dysplasia

Women having an abnormal Pap smear may be diagnosed with mild cervical dysplasia. Cervical dysplasia is a term to describe disordered cell growth on the cervix. Depending on the amount and special characteristics of changed cells this condition is classified as mild, moderate or severe dysplasia. Cervical dysplasia is a precancerous disease and, if not detected and treated in time, it may progress to cervical cancer.

Mild cervical dysplasia is diagnosed when abnormal changes involve about one third of squamous epithelium. If abnormal cells involve one half of the epithelium, the condition is classified as moderate cervical dysplasia. In cases of severe dysplasia the entire thickness of epithelial layer consists of abnormal changes. If abnormal cells cross the basement membrane and spread to other layers of the cervix, this condition is called invasive carcinoma or cancer.  

It was found that cervical dysplasia is often associated with Human Papilloma Virus (HPV). This virus infects epithelial layers in different parts of the body and may cause cellular changes. A typical manifestation of HPV infection is the occurrence of warts, benign tumors. But some HPV types, like HPV 16 and 18, are able to induce mild cervical dysplasia which may lead to cancer with time. Therefore, in order to evaluate the risk for cervical cancer it is often recommended to obtain an HPV DNA test.

Women having a diagnosis of mild cervical dysplasia should undergo a follow-up Pap smear in three or six months. In a majority of cases mild dysplasia disappears without any treatment. If mild dysplasia persists and is detected during follow-up examination, a woman should have additional diagnostic procedures like colposcopy and HPV DNA test.  

As compared to mild cervical dysplasia, moderate and severe lesions are less likely to regress on their own. When Pap smear results are suggestive of moderate or severe dysplasia, a biopsy should be done to confirm this diagnosis. If the diagnosis is confirmed, cervical lesions may require surgical removal by cryotherapy, laser, electrical loop or cold knife. The necessity of surgery and an appropriate treatment should be determined by a specialist that can assess all risks and all problems of the patient.

Risk factors for cervical dysplasia and cervical cancer include a high number of deliveries, history of sexually transmitted infections, having multiple sexual partners, smoking (active or passive), weakened immune system, first intercourse at an early age (before 16), history of abnormal Pap smear and others. Women with mild cervical dysplasia should undergo a close follow-up if some of these risk factors are present.

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HPV
Cervical Dysplasia
Genital Warts
Plantar Warts
Genital Herpes
Oral Herpes
Other Conditions


Dr. Joe Glickman, Jr., M.D.

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