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- Cervical Dysplasia - Cervical dysplasia means that there is abnormal cell growth (dysplasia) in the cervix. The cervix is the firm, smooth organ that forms the entrance to the uterus in the female reproductive system. Cell growth is considered abnormal when some areas of cervical cells are immature compared with their normal neighbors. They also divide faster than expected, and their nuclei show specific types of microscopic changes. Cervical dysplasia is an important health problem because it sometimes, but not always, progresses to cervical cancer.
Cervical dysplasia is a laboratory diagnosis made on the tiny sample of cervical tissue taken for a Pap smear. Depending on the specific naming system used, cervical dysplasia may also be calledsquamous intraepithelial lesion (SIL) or cervical intraepithelialneoplasia (CIN). When a Pap smear is examined under a microscope and abnormal cervical cells involve the lower third of the specimen, the condition is described as "mild" cervical dysplasia (low-grade SIL or CIN 1). If abnormal cervical cells are found on larger portions of the specimen, the condition is described as "moderate" or "severe" cervical dysplasia (high-grade SIL or CIN 2 or 3).
- Cervical Dysplasia - Treatments - less common treatments for warts include the drugs 5-FU (5-fluorouracil) and Interferon-alpha. 5-FU exists in a cream form. Interferon must be injected into the warts. A new drug, imiquimod (AldaraR), has been approved for treatment of genital warts. Cidofovir (VistideR), originally developed to fight cytomegalovirus (CMV), might also help fight HPV. A new drug called HspE7 has shown benefits in early research.
HPV infection can last for a long time, especially in people who are HIV-positive. Dysplasia and warts can return. They should be treated as soon as they are found to reduce the chances of the problem spreading or returning.
- Cervical Dysplasia - HPV, or Human Papilloma Virus is commonly called the wart virus. There are over 60 types of HPV that have been identified. Types 1, 3 and 5 can cause warts on the hands and feet of children. Types 6 and 11 can cause warts on men's and women's bottoms (genital warts). Other types, such as 16, 18, 31, 33, and 35 may not cause warts but can cause changes to the cells of your vagina or cervix, such as dysplasia.
Cervical dysplasia is a premalignant or precancerous change to the cells of your cervix. There are three types of cervical dysplasia: mild, moderate, and severe. Mild dysplasia is by far the most common, and probably is not a true premalignant disease. Mild dysplasia generally represents a tissue response to the HPV virus. Up to 70% of women with mild dysplasia will have the cells become normal without any treatment. However, even mild dysplasia can progress to more significant disease. Moderate and severe dysplasia are treated when they are discovered, because of their higher rates of turning into cancer.
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